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Total 122782 results found since Jan 2013.

SFBC guidelines on critical care testing.
Abstract SFBC working group on critical care testing describes in this paper guideline for the management of laboratory medicine examination process in emergency conditions. After a summary on French standards and regulations, the critical care testing perimeter and definitions of stat levels are presented in different contexts. The complete examination process is described. Guidelines are proposed for each step, to manage sub-process in a risk management approach. The following steps were studied: ordering (by specialties), sampling, transport, reception, analysis, validation and release. In summary, we proposed ...
Source: Annales de Biologie Clinique - March 31, 2016 Category: Biochemistry Authors: Vaubourdolle M, Alvarez JC, Barbé F, Beaudeux JL, Boissier É, Caillon H, Chatron P, Joly-Guillou ML, Mailloux A Tags: Ann Biol Clin (Paris) Source Type: research

The rise of mitochondria in medicine
Publication date: Available online 14 July 2016 Source:Mitochondrion Author(s): Martin Picard, Douglas C. Wallace, Yan Burelle Once considered exclusively the cell's powerhouse, mitochondria are now recognized to perform multiple essential cellular functions beyond energy production, impacting most areas of cell biology and medicine. Since the emergence of molecular biology and the discovery of pathogenic mitochondrial DNA defects in the 1980's, research advances have revealed a number of common human diseases which share an underlying pathogenesis involving mitochondrial dysfunction. Mitochondria undergo function-def...
Source: Mitochondrion - July 14, 2016 Category: Biochemistry Source Type: research

Impact of oligomeric enteral nutrition with low-molecular-weight whey peptides on diarrhea in critical care nutrition
In conclusion, Peptino‍® may be effective against diarrhea and gastrointestinal intolerance in critical care nutrition.PMID:36447482 | PMC:PMC9701588 | DOI:10.3164/jcbn.22-10
Source: Clinical Biochemistry - November 30, 2022 Category: Biochemistry Authors: Kensuke Nakamura Tetsuro Kawakami Hiromu Naraba Maiko Motoki Daisuke Ikechi Hidehiko Nakano Masaki Mochizuki Yuji Takahashi Hideki Hashimoto Source Type: research

6(th) International symposium « Critical care testing and blood gases ».
PMID: 26489815 [PubMed - as supplied by publisher]
Source: Annales de Biologie Clinique - October 1, 2015 Category: Biochemistry Authors: Feuillu SA Tags: Ann Biol Clin (Paris) Source Type: research

About the SFBC recommendations on critical care testing.
Authors: PMID: 29862975 [PubMed - in process]
Source: Annales de Biologie Clinique - June 1, 2018 Category: Biochemistry Tags: Ann Biol Clin (Paris) Source Type: research

Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS)
Conclusion In summary, in our study an alteration of zinc status was related with the severity-of-illness scores and inflammation in critical ill patients since admission in ICU stay. SIRS caused a general shut-down of expression of zinc transporters in whole blood. That behavior was associated with severity and inflammation of patients at ICU admission regardless zinc status. We conclude that zinc transporters in blood might be useful indicators of severity of systemic inflammation and outcome for critically ill patients.
Source: Journal of Trace Elements in Medicine and Biology - June 16, 2018 Category: Biochemistry Source Type: research

Reconsideration of the immunotherapeutic pediatric safe dose levels of aluminum
Publication date: Available online 8 March 2018 Source:Journal of Trace Elements in Medicine and Biology Author(s): James Lyons-Weiler, Robert Ricketson FDA regulations require safety testing of constituent ingredients in drugs (21 CFR 610.15). With the exception of extraneous proteins, no component safety testing is required for vaccines or vaccine schedules. The dosing of aluminum in vaccines is based on the production of antibody titers, not safety science. Here we estimate a Federal Pediatric Dose Limit that considers body weight. We identify several serious historical missteps in past analyses of provisional safe lev...
Source: Journal of Trace Elements in Medicine and Biology - March 9, 2018 Category: Biochemistry Source Type: research

Serum trace elements profile in the pediatric inflammatory bowel disease progress evaluation
CONCLUSIONAlthough much more studies are required on the subject our results demonstrate a clinical value of ETEs serum concentration profile in pediatric IBD patients regarding disease development.
Source: Journal of Trace Elements in Medicine and Biology - June 20, 2019 Category: Biochemistry Source Type: research

Feasibility of the use of a handheld XRF analyzer to measure skin iron to monitor iron levels in critical organs
In conclusion, skin iron XRF measurements can act as a surrogate marker for liver iron content, and can be measured using a commercial XRF device for a portable, fast, and non-invasive measurement.
Source: Journal of Trace Elements in Medicine and Biology - July 27, 2018 Category: Biochemistry Source Type: research

Human exposure to trace elements via farmed and cage aggregated wild Axillary seabream (Pagellus acarne) in a copper alloy cage site in the Northern Aegean Sea
Publication date: Available online 27 July 2018Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): Murat Yigit, Robert L. Dwyer, Barbaros Celikkol, Sevdan Yilmaz, Musa Bulut, Yesim Buyukates, Osman S. Kesbic, Umit Acar, Baris Ozalp, Masashi Maita, Sebahattin ErgünAbstractAxillary seabream (Pagellus acarne) farmed in a copper alloy mesh pen and wild individuals of P. acarne aggregated near the copper-alloy cages presented higher concentrations of trace metals in the liver, skin and gills than in fish muscle tissues in two batches of small and large fish sizes. Elevated mean levels of metals (mg kg-1) in mus...
Source: Journal of Trace Elements in Medicine and Biology - July 28, 2018 Category: Biochemistry Source Type: research

The novel metallo- β -lactamase PNGM-1 from a deep-sea sediment metagenome: crystallization and X-ray crystallographic analysis
In this study, PNGM-1 was overexpressed, purified and crystallized. Crystals of native and selenomethionine-substituted PNGM-1 diffracted to 2.10 and 2.30   Å resolution, respectively. Both the native and the selenomethionine-labelled PNGM-1 crystals belonged to the monoclinic space group P21, with unit-cell parameters a = 122, b = 83, c = 163   Å , β = 110 ° . Matthews coefficient (VM) calculations suggested the presence of 6 – 10 molecules in the asymmetric unit, corresponding to a solvent content of ∼ 31 – 58%. Structure determination is currently in progress.
Source: Acta Crystallographica Section F - September 19, 2018 Category: Biochemistry Authors: Park, K.S. Hong, M.-K. Jeon, J.W. Kim, J.H. Jeon, J.H. Lee, J.H. Kim, T.Y. Karim, A.M. Malik, S.K. Kang, L.-W. Lee, S.H. Tags: deep-sea sediment Edison Seamount metagenome antibiotic resistance metallo- β -lactamase research communications Source Type: research

The effects of iron and zinc status on prognosis in pediatric Wilson’s disease
ConclusionOur study suggests that SFr, SCu, SZn levels might have prognostic importance for WD.
Source: Journal of Trace Elements in Medicine and Biology - May 25, 2019 Category: Biochemistry Source Type: research

Trace elements in the muscle, ova and seminal fluid of key clupeid representatives from the Gdansk Bay (South Baltic Sea) and Iberian Peninsula (North-East Atlantic)
Publication date: Available online 4 June 2021Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): Andrzej R. Reindl, Lucyna Falkowska
Source: Journal of Trace Elements in Medicine and Biology - June 6, 2021 Category: Biochemistry Source Type: research